Simplified hierarchical linear models for the evaluation of surrogate endpoints

DOI10.1080/0094965031000062177MaRDI QIDQ4432903zbMATH OpenOpenAlexWikidataFDO

Authors Fabián S. Tibaldi, José Cortiñas Abrahantes, Geert Molenberghs, Tomasz Burzykowski, Marc Buyse, Max Parmar, T. Stijnen, Russ Wolfinger, Didier Renard

Publication date 29 October 2003

Published in Journal of Statistical Computation and Simulation (Search for Journal in Brave)

Full work available at URL http://hdl.handle.net/1942/421

Mathematics Subject Classification ID

Linear regression; mixed models (62J05)

Cited in

(13)

• Flexible surrogate marker evaluation from several randomized clinical trials with continuous endpoints, using R and SAS
• Center-within-trial versus trial-level evaluation of surrogate endpoints
• Simplified modeling strategies for surrogate validation with multivariate failure-time data
• The meta-analytic framework for the evaluation of surrogate endpoints in clinical trials
• Statistical evaluation of surrogate endpoints with examples from cancer clinical trials
• Validation of Surrogate Markers in Multiple Randomized Clinical Trials with Repeated Measurements: Canonical Correlation Approach
• On the relationship between the causal-inference and meta-analytic paradigms for the validation of surrogate endpoints
• Unbalanced cluster sizes and rates of convergence in mixed-effects models for clustered data
• Exploring the relationship between the causal-inference and meta-analytic paradigms for the evaluation of surrogate endpoints
• Differences in surrogate threshold effect estimates between original and simplified correlation-based validation approaches
• An information-theoretic approach to surrogate-marker evaluation with failure time endpoints
• Choice of units of analysis and modeling strategies in multilevel hierarchical models
• Using earlier measures in a longitudinal sequence as a potential surrogate for a later one

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