A Latent Variable Model of Segregation Analysis for Ordinal Traits

DOI10.1198/016214503000000981zbMATH Open1045.62115OpenAlexW1980365517MaRDI QIDQ4468552FDOQ4468552

Authors Heping Zhang, Rui Feng, Hongtu Zhu

Publication date 10 June 2004

Published in Journal of the American Statistical Association (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1198/016214503000000981

zbMATH Keywords

EM algorithmmixture modellatent variablefrailtysegregation analysisalcoholismpeeling algorithm

Mathematics Subject Classification ID

Parametric hypothesis testing (62F03) Asymptotic properties of parametric estimators (62F12) Applications of statistics to biology and medical sciences; meta analysis (62P10)

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Cited in

(9)

• Asymptotics for estimation and testing procedures under loss of identifiability
• Testing for two states in a hidden Markov model
• Testing for two components in a switching regression model
• Solving genetic heterogeneity in extended families by identifying sub-types of complex diseases
• Latent variable modeling paradigms for genotype-trait association studies
• The limiting bound of Efron's W-formula for hypothesis testing when a nuisance parameter is present only under the alternative
• ASSESSING FAMILIAL AGGREGATION WITH AN ORDINAL RESPONSE
• Statistical analysis in genetic studies of mental illnesses
• Generalized score test of homogeneity for mixed effects models

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