Global stochastic optimization in hierarchical modeling of ligand/protein binding profiles

DOI10.1108/03684920010322217MaRDI QIDQ4503201zbMATH OpenOpenAlexFDO

Authors Alexander D. Varshavsky, Duane T. Birnbaum, John M. Beals, Bo E. H. Saxberg

Publication date 21 November 2001

Published in Kybernetes (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1108/03684920010322217

zbMATH Keywords

numerical optimizationnonlinear fittinginsulin hexamerinsulin-ligand bindingligand-protein binding

Mathematics Subject Classification ID

Numerical mathematical programming methods (65K05) Applications of mathematical programming (90C90) Biochemistry, molecular biology (92C40) Stochastic programming (90C15)

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Cited in

(2)

• Global minimization and parameter estimation in computational biology.
• Global optimization in protein docking using clustering, underestimation and semidefinite programming

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