DESIGNS FOR TESTING LACK OF FIT FOR A NONLINEAR DOSE-RESPONSE CURVE MODEL

DOI10.1081/BIP-100101012MaRDI QIDQ4512650zbMATH OpenOpenAlexWikidataFDO

Authors Paul J. Lupinacci, D. Raghavarao

Publication date 5 November 2000

Published in Journal of Biopharmaceutical Statistics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1081/bip-100101012

zbMATH Keywords

D-optimalitynonlinear regressiondose-response functionGauss-Newtonlogistic functionRichard's family of growth curves

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05)

Recommendations

• Robustness of Design in Dose–Response Studies
• Optimal designs which are efficient for lack of fit tests
• Locally optimal designs for some dose-response models with continuous endpoints
• scientific article; zbMATH DE number 774838
• Robust designs for dose-response studies: model and labelling robustness

Cites work

• DESIGN OF EXPERIMENTS IN NON-LINEAR SITUATIONS
• Nonlinear Statistical Models for the Joint Action of Toxins

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