Robustness of Design in Dose–Response Studies

DOI10.1111/J.1467-9868.2010.00763.XMaRDI QIDQ4631608zbMATH OpenOpenAlexFDO

Authors Douglas P. Wiens, Pengfei Li

Publication date 12 April 2019

Published in Journal of the Royal Statistical Society Series B: Statistical Methodology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1111/j.1467-9868.2010.00763.x

zbMATH Keywords

\(\mathrm{ED}_{50}\)binarycontiguitydose-responsegeneralized linear modelKolmogorov neighbourhoodlogisticminimaxprobitquadratic programmingscoringsimulated annealing

Mathematics Subject Classification ID

Asymptotic properties of parametric estimators (62F12) Asymptotic properties of nonparametric inference (62G20) Nonparametric robustness (62G35) Generalized linear models (logistic models) (62J12) Optimal statistical designs (62K05) Applications of statistics to biology and medical sciences; meta analysis (62P10)

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• Choice of Number of Doses for Maximum Likelihood Estimation of the ED50 for Quantal Dose-Response Data
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• On generalized multinomial models and joint percentile estimation
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• Robust Procedures for Drug Combination Problems with Quantal Responses
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• Regularized robust estimation in binary regression models
• Bayesian optimum accelerated life test plans based on quantile regression
• Minimax robust designs for wavelet estimation of nonparametric regression models with autocorrelated errors
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• Designing group dose-response studies in the presence of transmission
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• Robust designs for generalized linear models with possible overdispersion and misspecified link functions

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