Choice of Number of Doses for Maximum Likelihood Estimation of the ED50 for Quantal Dose-Response Data

DOI10.2307/2531635MaRDI QIDQ3201562zbMATH OpenOpenAlexWikidataFDO

Authors Thomas Schmitt, Hans-Georg Müller

Publication date 1990

Published in Biometrics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.2307/2531635

zbMATH Keywords

maximum likelihood methodinformation matrixbioassayasymptotic mean squared errormedian effective doseED50allocation of dosesdesign densitiessymmetric dose- response curve

Mathematics Subject Classification ID

Point estimation (62F10) Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05)

Recommendations

• Selection of number of dose levels and its robustness for binary response data
• Likelihood‐Based Experimental Design for Estimation of Ed 50
• Robustness of Design in Dose–Response Studies
• Nonparametric estimation of dose-response curves with application to ED50 estimation
• THE DISTRIBUTION OF THE MAXIMUM LIKELIHOOD ESTIMATOR IN UP-AND-DOWN EXPERIMENTS FOR QUANTAL DOSE-RESPONSE DATA

Cited in

(7)

• Robust designs for dose-response studies: model and labelling robustness
• A two-stage hybrid procedure for estimating an inverse regression function
• Should we take measurements at an intermediate design point?
• Likelihood‐Based Experimental Design for Estimation of Ed 50
• THE DISTRIBUTION OF THE MAXIMUM LIKELIHOOD ESTIMATOR IN UP-AND-DOWN EXPERIMENTS FOR QUANTAL DOSE-RESPONSE DATA
• Robustness of interval estimation of the 90% effective dose: Bootstrap resampling and some large-sample parametric methods
• Selection of number of dose levels and its robustness for binary response data

This page was built for publication: Choice of Number of Doses for Maximum Likelihood Estimation of the ED50 for Quantal Dose-Response Data

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q3201562)