The deterministic limit of the Moran model: a uniform central limit theorem

MaRDI QIDQ4596938zbMATH OpenFDO

Authors

Publication date 11 December 2017

Full work available at URL https://arxiv.org/abs/1508.05231

zbMATH Keywords

central limit theoremMoran modelmutation-selection modelsdensity dependent populationslimit of large populations

Mathematics Subject Classification ID

Applications of continuous-time Markov processes on discrete state spaces (60J28) Genetics and epigenetics (92D10) Problems related to evolution (92D15) Central limit and other weak theorems (60F05) Continuous-time Markov processes on discrete state spaces (60J27)

Abstract: We consider a Moran model with two allelic types, mutation and selection. In this work, we study the behaviour of the proportion of fit individuals when the size of the population tends to infinity, without any rescaling of parameters or time. We first prove that the latter converges, uniformly in compacts in probability, to the solution of an ordinary differential equation, which is explicitly solved. Next, we study the stability properties of its equilibrium points. Moreover, we show that the fluctuations of the proportion of fit individuals, after a proper normalization, satisfy a uniform central limit theorem in $[0,infty)$. As a consequence, we deduce the convergence of the corresponding stationary distributions.

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(11)

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