The deterministic limit of the Moran model: a uniform central limit theorem

zbMATH Open1379.92035arXiv1508.05231MaRDI QIDQ4596938FDOQ4596938

Authors:

Publication date: 11 December 2017

Abstract: We consider a Moran model with two allelic types, mutation and selection. In this work, we study the behaviour of the proportion of fit individuals when the size of the population tends to infinity, without any rescaling of parameters or time. We first prove that the latter converges, uniformly in compacts in probability, to the solution of an ordinary differential equation, which is explicitly solved. Next, we study the stability properties of its equilibrium points. Moreover, we show that the fluctuations of the proportion of fit individuals, after a proper normalization, satisfy a uniform central limit theorem in $[0,infty)$. As a consequence, we deduce the convergence of the corresponding stationary distributions.

Full work available at URL: https://arxiv.org/abs/1508.05231

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zbMATH Keywords

central limit theoremMoran modelmutation-selection modelsdensity dependent populationslimit of large populations

Mathematics Subject Classification ID

Applications of continuous-time Markov processes on discrete state spaces (60J28) Genetics and epigenetics (92D10) Problems related to evolution (92D15) Central limit and other weak theorems (60F05) Continuous-time Markov processes on discrete state spaces (60J27)

Cited In (11)

• Solving the selection-recombination equation: ancestral lines and dual processes
• On the stationary distribution of the block counting process for population models with mutation and selection
• Fluctuations analysis of finite discrete birth and death chains with emphasis on Moran models with mutations
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• Common ancestor type distribution: a Moran model and its deterministic limit
• Title not available (Why is that?)
• Lines of descent in the deterministic mutation-selection model with pairwise interaction
• A probabilistic view on the deterministic mutation-selection equation: dynamics, equilibria, and ancestry via individual lines of descent
• Lookdown model with selection and mutation
• Uniform in time propagation of chaos for a Moran model
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