Rational design of antibiotic treatment plans: a treatment strategy for managing evolution and reversing resistance

DOI10.1371/JOURNAL.PONE.0122283zbMATH Open1375.92032OpenAlexW1925318597WikidataQ35623227 ScholiaQ35623227MaRDI QIDQ4599258FDOQ4599258

Authors Portia Mira, Kristina Crona, Devin C. V. Greene, Juan C. Meza, Bernd Sturmfels, Miriam Barlow 

Publication date 18 December 2017

Published in PLOS ONE (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1371/journal.pone.0122283

zbMATH Keywords

correlated probability modelequal probability model

Mathematics Subject Classification ID

Medical applications (general) (92C50) Problems related to evolution (92D15)

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• A stochastic programming approach to the antibiotics time machine problem
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• The geometry of partial fitness orders and an efficient method for detecting genetic interactions
• Bioaugmentation approaches for suppression of antibiotic resistance: model-based design
• Optimization problems involving matrix multiplication with applications in materials science and biology

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