Bacterial fitness shapes the population dynamics of antibiotic-resistant and -susceptible bacteria in a model of combined antibiotic and anti-virulence treatment

DOI10.1016/j.jtbi.2015.02.011zbMath1342.92104arXiv1409.4238OpenAlexW2064252738WikidataQ39626504 ScholiaQ39626504MaRDI QIDQ530477

Anne-Marie Krachler, Rosemary J. Dyson, Sara Jabbari, Lucy Ternent

Publication date: 1 August 2016

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1409.4238

zbMATH Keywords

antibiotic resistanceanti-virulence drugsbacterial population dynamics

Mathematics Subject Classification ID

Medical applications (general) (92C50) Physiological, cellular and medical topics (92C99)

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Cites Work

• The pharmacodynamics of antibiotic treatment
• Exploring the role of the immune response in preventing antibiotic resistance
• A new modeling approach to the effect of antimicrobial agents on heterogeneous microbial populations
• Mathematical model of a three-stage innate immune response to a pneumococcal lung infection
• The dynamics of bacterial infection, innate immune response, and antibiotic treatment