Bandit strategies evaluated in the context of clinical trials in rare life-threatening diseases

DOI10.1017/S0269964817000146MaRDI QIDQ4629422zbMATH OpenOpenAlexWikidataFDO

Authors Sofía S. Villar

Publication date 27 March 2019

Published in Probability in the Engineering and Informational Sciences (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.1017/s0269964817000146

zbMATH Keywords

heuristicsGittins indexWhittle indexpatient benefit-led trial designs

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50) Optimal statistical designs (62K05)

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• Choosing sample size for a clinical trial using decision analysis
• Computing a classic index for finite-horizon bandits
• Contributions to the "Two-Armed Bandit" Problem
• Multi-armed bandit allocation indices. With a foreword by Peter Whittle.
• Multi-armed bandit models for the optimal design of clinical trials: benefits and challenges
• On an index policy for restless bandits
• Optimal adaptive randomized designs for clinical trials
• Response-adaptive randomization for multi-arm clinical trials using the forward looking Gittins index rule
• Restless bandits, partial conservation laws and indexability

Cited in

(5)

• Multi-armed bandit models for the optimal design of clinical trials: benefits and challenges
• Implementing unequal randomization in clinical trials with heterogeneous treatment costs
• An Approximation Approach for Response-Adaptive Clinical Trial Design
• Response-adaptive randomization for multi-arm clinical trials using the forward looking Gittins index rule
• Generalisations of a Bayesian decision-theoretic randomisation procedure and the impact of delayed responses

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