Response-adaptive randomization for multi-arm clinical trials using the forward looking Gittins index rule

DOI10.1111/BIOM.12337MaRDI QIDQ2809522zbMATH OpenOpenAlexWikidataFDO

Authors Sofía S. Villar, Jack Bowden, James Wason

Publication date 30 May 2016

Published in Biometrics (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.1111/biom.12337

zbMATH Keywords

clinical trialsGittins indexmulti-armed banditsequential allocationBayesian adaptive designs

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05)

Recommendations

• Gittins indices and constrained allocation in clinical trials
• Bandit strategies evaluated in the context of clinical trials in rare life-threatening diseases
• Covariate-adjusted response-adaptive randomization for multi-arm clinical trials using a modified forward looking Gittins index rule
• Bayesian adaptive bandit-based designs using the Gittins index for multi-armed trials with normally distributed endpoints
• Publication:3033156

Cites work

• scientific article; zbMATH DE number 3148886 (Why is no real title available?)
• scientific article; zbMATH DE number 3690500 (Why is no real title available?)
• Implementing Optimal Allocation in Sequential Binary Response Experiments
• On the Gittins index in the M/G/1 queue
• Optimal adaptive designs for binary response trials
• Optimal adaptive randomized designs for clinical trials
• Optimality, Variability, Power
• Randomized allocation with nonparametric estimation for a multi-armed bandit problem with covariates
• The Theory of Response‐Adaptive Randomization in Clinical Trials

Cited in

(18)

• A simple solution to the inadequacy of asymptotic likelihood-based inference for response-adaptive clinical trials: likelihood-based inference for RAR trials
• Bandit strategies evaluated in the context of clinical trials in rare life-threatening diseases
• Generalisations of a Bayesian decision-theoretic randomisation procedure and the impact of delayed responses
• Response adaptive designs for phase II trials with binary endpoint based on context-dependent information measures
• Implementing unequal randomization in clinical trials with heterogeneous treatment costs
• Response-adaptive randomization in clinical trials: from myths to practical considerations
• Using biomarkers to allocate patients in a response-adaptive clinical trial
• A response-adaptive randomization procedure for multi-armed clinical trials with normally distributed outcomes
• Doubly adaptive biased coin design to improve Bayesian clinical trials with time-to-event endpoints
• A Bayesian adaptive design for clinical trials in rare diseases
• Rejoinder: response-adaptive randomization in clinical trials
• Response-adaptive randomization for multiarm clinical trials using context-dependent information measures
• The performance of fixed-horizon, look-ahead procedures compared to backward induction in Bayesian adaptive-randomization decision-theoretic clinical trial design
• Bayesian adaptive bandit-based designs using the Gittins index for multi-armed trials with normally distributed endpoints
• A Markov decision process for response-adaptive randomization in clinical trials
• A novel statistical test for treatment differences in clinical trials using a response‐adaptive forward‐looking Gittins Index Rule
• Covariate-adjusted response-adaptive randomization for multi-arm clinical trials using a modified forward looking Gittins index rule
• Gittins indices and constrained allocation in clinical trials

This page was built for publication: Response-adaptive randomization for multi-arm clinical trials using the forward looking Gittins index rule

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q2809522)