The Theory of Response‐Adaptive Randomization in Clinical Trials

DOI10.1002/047005588XzbMATH Open1111.62107MaRDI QIDQ5490901FDOQ5490901

Authors William F. Rosenberger, Feifang Hu 

Publication date 4 October 2006

Published in Wiley Series in Probability and Statistics (Search for Journal in Brave)

zbMATH Keywords

Sample size determinationML estimatorsUrn modelsSequential estimationClinical trials

Mathematics Subject Classification ID

Point estimation (62F10) Nonparametric estimation (62G05) Estimation in survival analysis and censored data (62N02) Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential estimation (62L12) Research exposition (monographs, survey articles) pertaining to statistics (62-02)

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Cited In (only showing first 100 items - show all)

• Title not available (Why is no real title available?)
• Longitudinal covariate-adjusted response-adaptive randomized designs
• Selecting a biased-coin design
• Response‐Adaptive Randomization for Clinical Trials with Continuous Outcomes
• On a notion of partially conditionally identically distributed sequences
• Statistical properties of two-color randomly reinforced urn design targeting fixed allocations
• Response adaptive designs for phase II trials with binary endpoint based on context-dependent information measures
• Sequential Monitoring of Conditional Randomization Tests: Generalized Biased Coin Designs
• Covariate-adaptive designs with missing covariates in clinical trials
• Efficient randomized-adaptive designs
• Multi-objective optimal designs in comparative clinical trials with covariates: the reinforced doubly adaptive biased coin design
• Asymptotic properties of covariate-adaptive randomization
• An optimal allocation for response-adaptive designs
• An optimal response adaptive biased coin design with \(k\) heteroscedastic treatments
• A new family of covariate-adjusted response adaptive designs and their properties
• Handling covariates in the design of clinical trials
• A Bayesian adaptive design for clinical trials in rare diseases
• Combination of Levene-type tests and a finite-intersection method for testing equality of variances against ordered alternatives
• Asymptotics in response-adaptive designs generated by a two-color, randomly reinforced urn
• Randomization in clinical trials. Theory and practice
• Optimal response-adaptive allocation designs in phase III clinical trials: incorporating ethics in optimality
• Sequential and two-stage fixed-width confidence interval estimation in response-adaptive designs
• A comparison of allocation strategies for optimising clinical trial designs under variance heterogeneity
• An optimal response-adaptive design with dual constraints
• Compound adaptive GPU design for clinical trials
• Response-Adaptive Randomization for Survival Trials: The Parametric Approach
• Randomised response-adaptive designs in clinical trials
• Implementing optimal allocation in clinical trials with multiple endpoints
• Immigrated urn models-theoretical properties and applications
• Interval estimation for response adaptive clinical trials
• Doubly adaptive biased coin designs with heterogeneous responses
• Response adaptive designs with misclassified responses
• Covariate-adjusted response-adaptive designs for generalized linear models
• On recent advances in optimal allocation designs in clinical trials
• Asymptotically best response-adaptive randomization procedures
• Drop-the-loser design in the presence of covariates
• Response-adaptive randomization for multi-arm clinical trials using the forward looking Gittins index rule
• A new design strategy for hypothesis testing under response adaptive randomization
• Web-based statistical tools for the analysis and design of clinical trials that incorporate historical controls
• A semiparametric sequential algorithm for estimation of dose-response curve
• Adaptative Designs for Multi-Arm Clinical Trials: The Play-the-Winner Rule Revisited
• Asymptotically efficient estimation in response adaptive trials
• Sequential monitoring of response-adaptive randomized clinical trials
• A randomized two stage allocation for continuous response clinical trials
• Implementing optimal allocation for sequential continuous responses with multiple treatments
• Covariate-adjusted response-adaptive randomization for multi-arm clinical trials using a modified forward looking Gittins index rule
• Novel Bayesian Adaptive Designs and Their Applications in Cancer Clinical Trials
• A response-driven adaptive design based on the Klein urn
• Inference after covariate-adaptive randomisation: aspects of methodology and theory
• Doubly adaptive biased coin designs with delayed responses
• On the almost sure convergence of adaptive allocation procedures
• The Gaussian approximation for multi-color generalized Friedman's urn model
• Response-adaptive treatment allocation for non-inferiority trials with heterogeneous variances
• Bayesian phase II adaptive randomization by jointly modeling time-to-event efficacy and binary toxicity
• Multiple-objective response-adaptive repeated measurement designs for clinical trials
• Some recent developments in the design of adaptive clinical trials
• Optimality, Variability, Power
• Adaptive Designs to Maximize Power in Clinical Trials with Multiple Treatments
• One-armed bandit process with a covariate
• Variance-penalized response-adaptive randomization with mismeasurement
• Mean and variance of balanced Pólya urns
• Statistical analysis of non-inferiority via non-zero risk difference in stratified matched-pair studies
• Adaptive crossover design for normal responses
• Sequential methods in multi-arm clinical trials
• Bayesian doubly adaptive randomization in clinical trials
• A covariate-adjusted response-adaptive allocation for a general class of continuous responses
• Asymptotic properties of multicolor randomly reinforced Pólya urns
• A general characterization of optimal tie-breaker designs
• A Markov decision process for response-adaptive randomization in clinical trials
• Nonparametric covariate-adjusted response-adaptive design based on a functional urn model
• An urn model to construct an efficient test procedure for response adaptive designs
• Matching on-the-fly: sequential allocation with higher power and efficiency
• On optimal designs for clinical trials: an updated review
• Asymptotic behavior of a randomization test for a response-adaptive design
• A two armed optimal response adaptive randomization for ordinal categorical responses with possible misclassification
• On the performance of the Neyman Allocation with small pilots
• A signature enrichment design with Bayesian adaptive randomization
• Randomization: the forgotten component of the randomized clinical trial
• A practical response adaptive block randomization (RABR) design with analytic type I error protection
• A simple solution to the inadequacy of asymptotic likelihood-based inference for response-adaptive clinical trials: likelihood-based inference for RAR trials
• A new inferential approach for response-adaptive clinical trials: the variance-stabilized bootstrap
• Power efficiency of Efron's biased coin design
• Covariate-adjusted response-adaptive designs based on semiparametric approaches
• Implementing unequal randomization in clinical trials with heterogeneous treatment costs
• The properties of entropy as a measure of randomness in a clinical trial
• Subgroup analysis and adaptive experiments crave for debiasing
• Exact statistical power for response adaptive designs
• A matching procedure for sequential experiments that iteratively learns which covariates improve power
• Generalized Efron's biased coin design and its theoretical properties
• An optimal sequential design in ethical allocation with an adaptive interim analysis
• Bayesian uncertainty directed trial designs
• Simulation of clinical trials: a review with emphasis on the design issues
• Doubly adaptive biased coin design to improve Bayesian clinical trials with time-to-event endpoints
• Clinical trials with exponential survival times
• Response-adaptive treatment allocation for clinical studies with recurrent event and terminal event data
• Allocation in platform trials to maintain comparability across time and eligibility
• Response adaptive intervention allocation in stepped-wedge cluster randomized trials
• A Bayesian-bandit adaptive design for \(N\)-of-1 clinical trials
• Optimal designs for testing the efficacy of heterogeneous experimental groups
• Stopping Rules in Balanced Allocation Problems: Exact and Asymptotic Distributions

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