Simulation of clinical trials: a review with emphasis on the design issues

DOI10.6092/ISSN.1973-2201/3634MaRDI QIDQ5148592zbMATH OpenOpenAlexFDO

Authors Alessandra Giovagnoli, Maroussa Zagoraiou

Publication date 4 February 2021

Full work available at URL https://ideas.repec.org/a/bot/rivsta/v72y2012i1p63-80.html

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

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Cites work

• A New ‘Biased Coin Design’ for the Sequential Allocation of Two Treatments
• Clinical Trials
• Computer experiments: a review
• Curve-free and model-based continual reassessment method designs
• Exact optimal designs for computer experiments via kriging metamodelling
• Forcing a sequential experiment to be balanced
• Fundamentals of clinical trials.
• scientific article; zbMATH DE number 1911987 (Why is no real title available?)
• scientific article; zbMATH DE number 2231192 (Why is no real title available?)
• Modification of Sample Size in Group Sequential Clinical Trials
• Optimum experimental designs, with SAS
• Randomized group up and down experiments
• Screening
• Statistical Issues in Drug Development
• The design and analysis of computer experiments.
• The Theory of Response‐Adaptive Randomization in Clinical Trials

Cited in

(6)

• Simulated clinical trials: principle, good practices, and focus on virtual patients generation
• Simulating economic factors in adjuvant breast cancer treatment
• Effective sample size estimation for a mechanical ventilation trial through Monte-Carlo simulation: length of mechanical ventilation and ventilator free days
• Bayesian sequential analysis of clinical trials feedback
• Let's practice what we preach: Planning and interpreting simulation studies with design and analysis of experiments
• Comment: is response-adaptive randomization a ``good thing or not in clinical trials? Why we cannot take sides

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