Response-adaptive treatment allocation for non-inferiority trials with heterogeneous variances

DOI10.1016/J.CSDA.2018.03.005MaRDI QIDQ1662866zbMATH OpenOpenAlexFDO

Authors Wenfu Xu, Jingya Gao, Siu Hung Cheung, Feifang Hu

Publication date 20 August 2018

Published in Computational Statistics and Data Analysis (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.csda.2018.03.005

zbMATH Keywords

familywise error rateadaptive designnon-inferiority trialsdoubly adaptive biased coin designheterogeneous variances

Mathematics Subject Classification ID

Computational methods for problems pertaining to statistics (62-08) Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05)

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Cites work

• scientific article; zbMATH DE number 1817583 (Why is no real title available?)
• A Comparison of Procedures for Multiple Comparisons of Means with Unequal Variances
• Asymptotic properties of covariate-adjusted response-adaptive designs
• Asymptotic properties of doubly adaptive biased coin designs for multitreatment clinical trials.
• Central limit theorems for doubly adaptive biased coin designs
• Challenges and regulatory experiences with non‐inferiority trial design without placebo arm
• Implementing Optimal Allocation in Sequential Binary Response Experiments
• Multiple contrast tests in the presence of heteroscedasticity
• Optimal adaptive randomized designs for clinical trials
• Optimality, Variability, Power
• The Theory of Response‐Adaptive Randomization in Clinical Trials
• The doubly adaptive biased coin design for sequential clinical trials

Cited in

(5)

• On Multi-Treatment Adaptive Allocation Design for Dichotomous Response
• Simultaneous tests of non inferiority and superiority in three-arm clinical studies with heterogeneous variance
• A comparison of allocation strategies for optimising clinical trial designs under variance heterogeneity
• Adaptive treatment allocation for comparative clinical studies with recurrent events data
• A randomized two stage allocation for continuous response clinical trials

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