Response-adaptive treatment allocation for non-inferiority trials with heterogeneous variances

DOI10.1016/J.CSDA.2018.03.005zbMATH Open1469.62167OpenAlexW2791637491MaRDI QIDQ1662866FDOQ1662866

Authors: Wenfu Xu, Jingya Gao, Siu Hung Cheung, Feifang Hu 

Publication date: 20 August 2018

Published in: Computational Statistics and Data Analysis (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.csda.2018.03.005

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zbMATH Keywords

familywise error rateadaptive designnon-inferiority trialsdoubly adaptive biased coin designheterogeneous variances

Mathematics Subject Classification ID

Computational methods for problems pertaining to statistics (62-08) Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05)

Cites Work

• Asymptotic properties of covariate-adjusted response-adaptive designs
• Title not available (Why is that?)
• The Theory of Response‐Adaptive Randomization in Clinical Trials
• Multiple Contrast Tests in the Presence of Heteroscedasticity
• Optimal adaptive randomized designs for clinical trials
• The doubly adaptive biased coin design for sequential clinical trials
• Asymptotic properties of doubly adaptive biased coin designs for multitreatment clinical trials.
• Optimality, Variability, Power
• Implementing Optimal Allocation in Sequential Binary Response Experiments
• Central limit theorems for doubly adaptive biased coin designs
• A Comparison of Procedures for Multiple Comparisons of Means with Unequal Variances
• Challenges and regulatory experiences with non‐inferiority trial design without placebo arm

Cited In (3)

• On Multi-Treatment Adaptive Allocation Design for Dichotomous Response
• Simultaneous tests of non inferiority and superiority in three-arm clinical studies with heterogeneous variance
• A randomized two stage allocation for continuous response clinical trials

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