Bayesian adaptive bandit-based designs using the Gittins index for multi-armed trials with normally distributed endpoints

DOI10.1080/02664763.2017.1342780MaRDI QIDQ5035752zbMATH OpenOpenAlexWikidataFDO

Authors Adam L. Smith, Sofía S. Villar

Publication date 22 February 2022

Published in Journal of Applied Statistics (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://arxiv.org/abs/1703.05172

zbMATH Keywords

Gittins indexmulti-armed banditpatient allocationresponse adaptive proceduressequential samplingnormally distributed endpoint

Mathematics Subject Classification ID

Applications of statistics (62Pxx)

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• Multi-armed bandit models for the optimal design of clinical trials: benefits and challenges
• One-armed bandit problems with covariates
• Probability, random processes, and statistical analysis.
• Randomised allocation of treatments in sequential trials
• Response-adaptive randomization for multi-arm clinical trials using the forward looking Gittins index rule
• The learning component of dynamic allocation indices
• The multi-armed bandit problem with covariates

Cited in

(8)

• Multi-armed bandit models for the optimal design of clinical trials: benefits and challenges
• A response-adaptive randomization procedure for multi-armed clinical trials with normally distributed outcomes
• Response-adaptive randomization for multi-arm clinical trials using the forward looking Gittins index rule
• Nonmyopic and pseudo-nonmyopic approaches to optimal sequential design in the presence of covariates
• Generalisations of a Bayesian decision-theoretic randomisation procedure and the impact of delayed responses
• Covariate-adjusted response-adaptive randomization for multi-arm clinical trials using a modified forward looking Gittins index rule
• A novel statistical test for treatment differences in clinical trials using a response‐adaptive forward‐looking Gittins Index Rule
• Rejoinder: response-adaptive randomization in clinical trials

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