Parameter Estimation of the Hodgkin--Huxley Gating Model: An Inversion Procedure

DOI10.1137/S0036139902419826MaRDI QIDQ4830583zbMATH OpenOpenAlexFDO

Authors Guanjun Wang, Jacques Beaumont

Publication date 13 December 2004

Published in SIAM Journal on Applied Mathematics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1137/s0036139902419826

zbMATH Keywords

inverse problemHodgkin-Huxley modelmembrane current kineticsnonlinear parameter estimation

Mathematics Subject Classification ID

Physiology (general) (92C30) Biological applications of optics and electromagnetic theory (78A70) Biophysics (92C05) Inverse theorems in approximation theory (41A27)

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(10)

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• Automated parameter estimation of the Hodgkin-Huxley model using the differential evolution algorithm: application to neuromimetic analog integrated circuits
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• Biophysically interpretable inference of single neuron dynamics
• Estimability analysis and optimal design in dynamic multi-scale models of cardiac electrophysiology
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• Diversity of traveling wave solutions in Fitzhugh-Nagumo type equations
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