On some statistical methods for analysis of combination drug studies∗

DOI10.1080/03610929408831260MaRDI QIDQ4843734zbMATH OpenOpenAlexFDO

Authors H. M. James Hung, G. Y. H. Chi, Raymond J. Lipicky

Publication date 17 August 1995

Published in Communications in Statistics: Theory and Methods (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1080/03610929408831260

zbMATH Keywords

AVE testconfidence regionconfidence surfacedose responsefactorial trialMAX testmin testresponse surfacetwo-stage test

Mathematics Subject Classification ID

Statistics (62-XX)

Recommendations

• Application of response surface methodology and factorial designs to clinical trials for drug combination development
• Testing for the Existence of a Desirable Dose Combination
• Statistical methods in drug combination studies
• Blends of statistical designs for dose-response studies¹
• scientific article; zbMATH DE number 44794

Cites work

• A new look at the statistical model identification
• A sharper Bonferroni procedure for multiple tests of significance
• Comparison of treatments in a combination therapy trial
• scientific article; zbMATH DE number 3913478 (Why is no real title available?)
• scientific article; zbMATH DE number 50804 (Why is no real title available?)
• scientific article; zbMATH DE number 3994822 (Why is no real title available?)
• On a Heuristic Method of Test Construction and its use in Multivariate Analysis
• Testing for the Existence of a Desirable Dose Combination
• Testing Whether an Identified Treatment Is Best

Cited in

(6)

• Choosing drugs in a matrix treatment model
• Application of response surface methodology and factorial designs to clinical trials for drug combination development
• Statistical methods in drug combination studies
• A note on tests for interaction in quantal response data
• Testing for the Existence of a Desirable Dose Combination
• On dose-response modeling for evaluation of drugs combinations

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