Optimal designs for two nested pharmacokinetic models with correlated observations

DOI10.1080/03610918.2012.625743MaRDI QIDQ4905893zbMATH OpenOpenAlexFDO

Authors Mariano Amo-Salas, Jesús López-Fidalgo, Víctor Ignacio López-Ríos

Publication date 21 February 2013

Published in Communications in Statistics. Simulation and Computation (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1080/03610918.2012.625743

zbMATH Keywords

\(T\)-optimalitycompartmental modelsFisher information matrixlikelihood rationsimulation

Mathematics Subject Classification ID

Optimal statistical designs (62K05) Applications of statistics to biology and medical sciences; meta analysis (62P10)

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Cites work

• DT-optimum designs for model discrimination and parameter estimation
• Experimental Design for Time-Dependent Models with Correlated Observations
• scientific article; zbMATH DE number 54240 (Why is no real title available?)
• Optimum Experimental Designs for Properties of a Compartmental Model
• Parameter Estimation for Nonlinear Models with Emphasis on Compartmental Models
• The design of experiments for discriminating between two rival models

Cited in

(8)

• Optimal designs for some stochastic processes whose covariance is a function of the mean
• Efficient algorithms for optimal designs with correlated observations in pharmacokinetics and dose-finding studies
• Optimal designs for compartmental models with correlated observations
• Optimal parametric design with applications to pharmacokinetic and pharmacodynamic trials
• Modification of the random differential transformation method and its applications to compartmental models
• OPTIMAL DESIGNS FOR SERIES ESTIMATION IN NONPARAMETRIC REGRESSION WITH CORRELATED DATA
• Optimal designs for random effect models with correlated errors with applications in population pharmacokinetics
• KL-optimal experimental design for discriminating between two growth models applied to a beef farm

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