Predicting tyrosinaemia: a mathematical model of 4-hydroxyphenylpyruvate dioxygenase inhibition by nitisinone in rats

DOI10.1093/IMAMMB/DQW006MaRDI QIDQ4968249zbMATH OpenOpenAlexWikidataFDO

Authors J. Ward, J. L. Dunster, Pratibha Mistry, José Domingo Salazar, Gianne Derks

Publication date 12 July 2019

Published in Mathematical Medicine and Biology (Search for Journal in Brave)

Full work available at URL https://figshare.com/articles/Predicting_tyrosinaemia_a_mathematical_model_of_4-hydroxyphenylpyruvate_dioxygenase_inhibition_by_nitisinone_in_rats/9387356

zbMATH Keywords

asymptotic analysismathematical modelrat4-hydroxyphenylpyruvate dioxygenasePBPK/PDtyrosinaemia

Mathematics Subject Classification ID

Medical applications (general) (92C50) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

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