Identifiability of stochastically modelled reaction networks
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Abstract: Chemical reaction networks describe interactions between biochemical species. Once an underlying reaction network is given for a biochemical system, the system dynamics can be modelled with various mathematical frameworks such as continuous time Markov processes. In this manuscript, the identifiability of the underlying network structure with a given stochastic system dynamics is studied. It is shown that some data types related to the associated stochastic dynamics can uniquely identify the underlying network structure as well as the system parameters. The accuracy of the presented network inference is investigated when given dynamical data is obtained via stochastic simulations.
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Cited in
(15)- Identifiability from a few species for a class of biochemical reaction networks
- Identification of alterations in the Jacobian of biochemical reaction networks from steady state covariance data at two conditions
- Reaction-diffusion systems in protein networks: global existence and identification
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