Identifiability of stochastically modelled reaction networks
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Publication:5014473
DOI10.1017/S0956792520000492zbMATH Open1478.92068arXiv2006.02272OpenAlexW3129855824MaRDI QIDQ5014473FDOQ5014473
Authors: Germán A. Enciso, Radek Erban, Jinsu Kim 
Publication date: 8 December 2021
Published in: European Journal of Applied Mathematics (Search for Journal in Brave)
Abstract: Chemical reaction networks describe interactions between biochemical species. Once an underlying reaction network is given for a biochemical system, the system dynamics can be modelled with various mathematical frameworks such as continuous time Markov processes. In this manuscript, the identifiability of the underlying network structure with a given stochastic system dynamics is studied. It is shown that some data types related to the associated stochastic dynamics can uniquely identify the underlying network structure as well as the system parameters. The accuracy of the presented network inference is investigated when given dynamical data is obtained via stochastic simulations.
Full work available at URL: https://arxiv.org/abs/2006.02272
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Biochemistry, molecular biology (92C40) Systems biology, networks (92C42) Applications of stochastic analysis (to PDEs, etc.) (60H30)
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Cited In (14)
- Stochastically modeled weakly reversible reaction networks with a single linkage class
- Identifiability from a few species for a class of biochemical reaction networks
- Learning chemical reaction networks from trajectory data
- Parameter estimation for models of chemical reaction networks from experimental data of reaction rates
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