Bifurcation and Potential Landscape of p53 Dynamics Depending on PDCD5 Level and ATM Degradation Rate

DOI10.1142/S0218127420501345zbMath1451.37111OpenAlexW3047757892MaRDI QIDQ5120533

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Publication date: 15 September 2020

Published in: International Journal of Bifurcation and Chaos (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1142/s0218127420501345

zbMATH Keywords

bifurcationpotential landscapeATM degradation ratep53 dynamics

Mathematics Subject Classification ID

Dynamical systems in biology (37N25) Medical applications (general) (92C50) Cell movement (chemotaxis, etc.) (92C17)

Related Items (4)

Stability and bifurcation analyses of p53 gene regulatory network with time delay ⋮ Modulation instability analysis of Rossby waves based on (2 + 1)-dimensional high-order Schrödinger equation ⋮ Modeling the roles of 14-3-3 σ and Wip1 in p53 dynamics and programmed cell death* ⋮ Multiple Time Delays Induced Dynamics of p53 Gene Regulatory Network

Uses Software

• XPPAUT

Cites Work

• PDCD5 functions as a regulator of p53 dynamics in the DNA damage response
• Stability switches, bifurcation, and multi-stability of coupled networks with time delays
• Simulating, Analyzing, and Animating Dynamical Systems
• Bifurcation analysis and potential landscapes of the p53-Mdm2 module regulated by the co-activator programmed cell death 5

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