Group Sequential and Adaptive Designs – A Review of Basic Concepts and Points of Discussion

DOI10.1002/bimj.200710436zbMath1442.62669OpenAlexW1997013447WikidataQ37229355 ScholiaQ37229355MaRDI QIDQ5123086

Marc Vandemeulebroecke

Publication date: 25 September 2020

Published in: Biometrical Journal (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1002/bimj.200710436

zbMATH Keywords

adaptive designgroup sequential designsequential analysisspending functioninterim analysisconditional error functioncombination testflexible designtrial integritytrial validity

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

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