Impact of different model structure and prior distribution in continual reassessment method

DOI10.1080/03610918.2018.1476698OpenAlexW2890200610MaRDI QIDQ5087922FDOQ5087922

Authors: Efehan Ulas, Filiz Karaman, Tuba Koç 

Publication date: 4 July 2022

Published in: Communications in Statistics. Simulation and Computation (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1080/03610918.2018.1476698

Recommendations

• Consistency of continual reassessment method under model misspecification
• A simple technique to evaluate model sensitivity in the continual reassessment method
• Characterization of the likelihood continual reassessment method
• A note on the robustness of the continual reassessment method
• Curve-free and model-based continual reassessment method designs

zbMATH Keywords

clinical trialsmaximum tolerated dosephase Idose-response models

Mathematics Subject Classification ID

Statistics (62-XX)

Cites Work

• Bayesian model averaging: A tutorial. (with comments and a rejoinder).
• Continual Reassessment Method: A Practical Design for Phase 1 Clinical Trials in Cancer
• Sequential Designs for Phase I Clinical Trials with Late‐Onset Toxicities
• Optimal Bayesian-feasible dose escalation for cancer phase I trials
• A Curve‐Free Method for Phase I Clinical Trials
• Bayesian Model Averaging Continual Reassessment Method in Phase I Clinical Trials
• Group Sequential and Adaptive Designs – A Review of Basic Concepts and Points of Discussion

Uses Software

• bcrm

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