Comparison of dichotomized and distributional approaches in rare event clinical trial design: a fixed Bayesian design

DOI10.1080/02664763.2016.1214244OpenAlexW2517218395WikidataQ38786837 ScholiaQ38786837MaRDI QIDQ5138641FDOQ5138641

Authors: Yang Lei, Susan Carlson, Lisa N. Yelland, Maria Makrides, Robert E. Gibson, Byron J. Gajewski 

Publication date: 4 December 2020

Published in: Journal of Applied Statistics (Search for Journal in Brave)

Full work available at URL: http://hdl.handle.net/2440/104981

Recommendations

• Sample size calculations for mixture alternatives in a control group vs. treatment group design
• Designing one-sided group sequential clinical trials to detect a mixture alternative
• Phase I (or Phase II) Dose-Ranging Clinical Trials: Proposal of a Two-Stage Bayesian Design
• Bayesian Adaptive Biased‐Coin Designs for Clinical Trials with Normal Responses
• Conditional analysis of mixed Poisson processes with baseline counts: implications for trial design and analysis

zbMATH Keywords

Bayesiansimulationdichotomizationnormal mixture modelpreterm birth

Mathematics Subject Classification ID

Statistics (62-XX)

Cites Work

• Finite mixture models
• A Comparison of Two Methods of Analysis of Mixtures of Normal Distributions
• Power considerations when a continuous outcome variable is dichotomized

Cited In (1)

• Bayesian design of superiority clinical trials for recurrent events data with applications to bleeding and transfusion events in myelodyplastic syndrome

This page was built for publication: Comparison of dichotomized and distributional approaches in rare event clinical trial design: a fixed Bayesian design

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q5138641)