A basic model of mutations

DOI10.1051/PS/2020024MaRDI QIDQ5140342zbMATH OpenOpenAlexFDO

Authors Maxime Berger, Raphaël Cerf

Publication date 15 December 2020

Published in ESAIM: Probability and Statistics (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://arxiv.org/abs/1806.01212

zbMATH Keywords

geneticsMarkov chaingenerating functionpotential theory

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Markov chains (discrete-time Markov processes on discrete state spaces) (60J10) Probabilistic potential theory (60J45)

Abstract: We study a basic model for mutations. We derive exact formulae for the mean time needed to discover the master sequence, the mean returning time to the initial state, or to any Hamming class. These last two formulae are the same than the formulae obtained by Mark Kac for the Ehrenfest model.

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Cites work

• scientific article; zbMATH DE number 3934150 (Why is no real title available?)
• scientific article; zbMATH DE number 3249395 (Why is no real title available?)
• Alternative Solution to the Ehrenfest Problem
• Exchangeable pairs of Bernoulli random variables, Krawtchouck polynomials, and Ehrenfest urns
• Random Walk and the Theory of Brownian Motion

Cited in

(2)

• First and second moments and the mean Hamming distance in a stochastic replication-mutation model for biological macromolecules
• A spectral decomposition for a simple mutation model

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