A basic model of mutations

DOI10.1051/PS/2020024zbMATH Open1455.60094arXiv1806.01212OpenAlexW3088888339MaRDI QIDQ5140342FDOQ5140342

Authors: Maxime Berger, Raphaël Cerf 

Publication date: 15 December 2020

Published in: ESAIM: Probability and Statistics (Search for Journal in Brave)

Abstract: We study a basic model for mutations. We derive exact formulae for the mean time needed to discover the master sequence, the mean returning time to the initial state, or to any Hamming class. These last two formulae are the same than the formulae obtained by Mark Kac for the Ehrenfest model.

Full work available at URL: https://arxiv.org/abs/1806.01212

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zbMATH Keywords

geneticsMarkov chaingenerating functionpotential theory

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Markov chains (discrete-time Markov processes on discrete state spaces) (60J10) Probabilistic potential theory (60J45)

Cites Work

• Title not available (Why is that?)
• Title not available (Why is that?)
• Exchangeable pairs of Bernoulli random variables, Krawtchouck polynomials, and Ehrenfest urns
• Random Walk and the Theory of Brownian Motion
• Alternative Solution to the Ehrenfest Problem

Cited In (2)

• A spectral decomposition for a simple mutation model
• First and second moments and the mean Hamming distance in a stochastic replication-mutation model for biological macromolecules

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