Regression-adjusted average treatment effect estimates in stratified randomized experiments
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Publication:5145706
DOI10.1093/BIOMET/ASAA038zbMATH Open1457.62046arXiv1908.01628OpenAlexW3034992734MaRDI QIDQ5145706FDOQ5145706
Publication date: 21 January 2021
Published in: Biometrika (Search for Journal in Brave)
Abstract: Researchers often use linear regression to analyse randomized experiments to improve treatment effect estimation by adjusting for imbalances of covariates in the treatment and control groups. Our work offers a randomization-based inference framework for regression adjustment in stratified randomized experiments. Under mild conditions, we re-establish the finite population central limit theorem for a stratified experiment. We prove that both the stratified difference-in-means and the regression-adjusted average treatment effect estimators are consistent and asymptotically normal. The asymptotic variance of the latter is no greater and is typically lesser than that of the former. We also provide conservative variance estimators to construct large-sample confidence intervals for the average treatment effect.
Full work available at URL: https://arxiv.org/abs/1908.01628
randomized experimentsrandomization-based inferencestratified samplingblockingrandomized block design
Linear regression; mixed models (62J05) Sampling theory, sample surveys (62D05) Statistical block designs (62K10)
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- Comment on ‘Inference after covariate-adaptive randomisation: aspects of methodology and theory’
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- Stratified doubly robust estimators for the average causal effect
- Toward Better Practice of Covariate Adjustment in Analyzing Randomized Clinical Trials
- Rejoinder on ‘Inference after covariate-adaptive randomization: aspects of methodology and theory’
- Randomization-based Joint Central Limit Theorem and Efficient Covariate Adjustment in Randomized Block 2 K Factorial Experiments
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