Nonparametric Bayesian instrumental variable analysis: evaluating heterogeneous effects of coronary arterial access site strategies
From MaRDI portal
Publication:5146014
Abstract: Percutaneous coronary interventions (PCIs) are nonsurgical procedures to open blocked blood vessels to the heart, frequently using a catheter to place a stent. The catheter can be inserted into the blood vessels using an artery in the groin or an artery in the wrist. Because clinical trials have indicated that access via the wrist may result in fewer post procedure complications, shortening the length of stay, and ultimately cost less than groin access, adoption of access via the wrist has been encouraged. However, patients treated in usual care are likely to differ from those participating in clinical trials, and there is reason to believe that the effectiveness of wrist access may differ between males and females. Moreover, the choice of artery access strategy is likely to be influenced by patient or physician unmeasured factors. To study the effectiveness of the two artery access site strategies on hospitalization charges, we use data from a state-mandated clinical registry including 7,963 patients undergoing PCI. A hierarchical Bayesian likelihood-based instrumental variable analysis under a latent index modeling framework is introduced to jointly model outcomes and treatment status. Our approach accounts for unobserved heterogeneity via a latent factor structure, and permits nonparametric error distributions with Dirichlet process mixture models. Our results demonstrate that artery access in the wrist reduces hospitalization charges compared to access in the groin, with higher mean reduction for male patients.
Recommendations
- Double robust estimation for multiple unordered treatments and clustered observations: evaluating drug-eluting coronary artery stents
- A Comparison of Methods for Estimating the Causal Effect of a Treatment in Randomized Clinical Trials Subject to Noncompliance
- Detecting heterogeneous treatment effects with instrumental variables and application to the Oregon Health Insurance Experiment
- A semi-parametric Bayesian approach to the instrumental variable problem
- Bridging preference‐based instrumental variable studies and cluster‐randomized encouragement experiments: Study design, noncompliance, and average cluster effect ratio
Cites work
- A Bayesian analysis of some nonparametric problems
- Assessing the effect of an influenza vaccine in an encouragement design
- Bayesian analysis of cross-section and clustered data treatment models
- Bayesian data analysis.
- Bayesian treatment effects models with variable selection for panel outcomes with an application to earnings effects of maternity leave
- Bootstrap Tests for Distributional Treatment Effects in Instrumental Variable Models
- Estimation of Treatment Effects in Randomized Trials With Non-Compliance and a Dichotomous Outcome
- Gibbs Sampling Methods for Stick-Breaking Priors
- Identification of Causal Effects Using Instrumental Variables
- Independence, Monotonicity, and Latent Index Models: An Equivalence Result
- Marginal and nested structural models using instrumental variables
- Regression and weighting methods for causal inference using instrumental variables
- Treatment effects: a Bayesian perspective
Cited in
(2)
This page was built for publication: Nonparametric Bayesian instrumental variable analysis: evaluating heterogeneous effects of coronary arterial access site strategies
Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q5146014)
