Uncertainty and sensitivity analyses methods for agent-based mathematical models: an introductory review

DOI10.1142/9789811223495_0001MaRDI QIDQ5152183zbMATH OpenOpenAlexFDO

Authors

Publication date 17 September 2021

Published in The Physics of Cancer (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/1911.08429

zbMATH Keywords

sensitivity analysisagent-based modelsrobustness analysiscancer modelconsistency analysisLatin hypercube analysis

Mathematics Subject Classification ID

Computational methods for problems pertaining to statistics (62-08) Nonparametric robustness (62G35) Applications of statistics to biology and medical sciences; meta analysis (62P10) Statistical block designs (62K10) Orthogonal arrays, Latin squares, Room squares (05B15) Pathology, pathophysiology (92C32)

Abstract: Multiscale, agent-based mathematical models of biological systems are often associated with model uncertainty and sensitivity to parameter perturbations. Here, three uncertainty and sensitivity analyses methods, that are suitable to use when working with agent-based models, are discussed. These methods are namely Consistency Analysis, Robustness Analysis and Latin Hypercube Analysis. This introductory review discusses origins, conventions, implementation and result interpretation of the aforementioned methods. Information on how to implement the discussed methods in MATLAB is included.

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(5)

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Describes a project that uses

Uses Software

• Matlab

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