Uncertainty and sensitivity analyses methods for agent-based mathematical models: an introductory review

DOI10.1142/9789811223495_0001zbMATH Open1479.62088arXiv1911.08429OpenAlexW2991179912MaRDI QIDQ5152183FDOQ5152183

Authors:

Publication date: 17 September 2021

Published in: The Physics of Cancer (Search for Journal in Brave)

Abstract: Multiscale, agent-based mathematical models of biological systems are often associated with model uncertainty and sensitivity to parameter perturbations. Here, three uncertainty and sensitivity analyses methods, that are suitable to use when working with agent-based models, are discussed. These methods are namely Consistency Analysis, Robustness Analysis and Latin Hypercube Analysis. This introductory review discusses origins, conventions, implementation and result interpretation of the aforementioned methods. Information on how to implement the discussed methods in MATLAB is included.

Full work available at URL: https://arxiv.org/abs/1911.08429

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zbMATH Keywords

sensitivity analysisagent-based modelsrobustness analysiscancer modelconsistency analysisLatin hypercube analysis

Mathematics Subject Classification ID

Computational methods for problems pertaining to statistics (62-08) Nonparametric robustness (62G35) Applications of statistics to biology and medical sciences; meta analysis (62P10) Statistical block designs (62K10) Orthogonal arrays, Latin squares, Room squares (05B15) Pathology, pathophysiology (92C32)

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Uses Software

• Matlab

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