Cellular interactions constrain tumor growth

DOI10.1073/PNAS.1804150116MaRDI QIDQ5222783zbMATHOpenAlexWikidataFDO

Authors Jeffrey West, P. K. Newton

Publication date 3 July 2019

Published in Proceedings of the National Academy of Sciences (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1073/pnas.1804150116

Mathematics Subject Classification ID

Medical applications (general) (92C50) Systems biology, networks (92C42) Cell biology (92C37)

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(7)

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• A novel mathematical model of heterogeneous cell proliferation
• Why Increase of Heterogeneity Signals Pre-Deterioration During Tumor Progression: A Unified Mathematical Model
• Gompertzian growth as a consequence of tumor heterogeneity
• Spatial cumulant models enable spatially informed treatment strategies and analysis of local interactions in cancer systems
• Interlocking triads of growth control in tumors
• Do mechanisms matter? Comparing cancer treatment strategies across mathematical models and outcome objectives

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