Do mechanisms matter? Comparing cancer treatment strategies across mathematical models and outcome objectives

DOI10.3934/MBE.2021315MaRDI QIDQ2092087zbMATH OpenOpenAlexFDO

Authors Cassidy K. Buhler, Rebecca S. Terry, Kathryn G. Link, Frederick R. Adler

Publication date 2 November 2022

Published in Mathematical Biosciences and Engineering (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.3934/mbe.2021315

zbMATH Keywords

adaptive therapyAllee effectandrogen dynamicscancer ecologycompetitionmathematical model

Mathematics Subject Classification ID

Qualitative investigation and simulation of ordinary differential equation models (34C60) Medical applications (general) (92C50)

Cites work

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• Feedback regulation in a cancer stem cell model can cause an Allee effect
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• Limiting the development of anti-cancer drug resistance in a spatial model of micrometastases
• On drug resistance and metronomic chemotherapy: a mathematical modeling and optimal control approach
• Optimal control to develop therapeutic strategies for metastatic castrate resistant prostate cancer
• Populational adaptive evolution, chemotherapeutic resistance and multiple anti-cancer therapies
• Ultimate dynamics and optimal control of a multi-compartment model of tumor resistance to chemotherapy

Cited in

(3)

• Tumor containment: a more general mathematical analysis
• Public goods games in disease evolution and spread
• Bilinear controlled model in adaptive cancer therapy

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