Feedback regulation in a cancer stem cell model can cause an Allee effect

DOI10.1007/S11538-016-0161-5MaRDI QIDQ301562zbMATH OpenOpenAlexWikidataFDO

Authors Anna Konstorum, Thomas Hillen, John Lowengrub

Publication date 30 June 2016

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL http://europepmc.org/articles/pmc4946570

zbMATH Keywords

Allee effectcancer stem celltumor extinctionstable manifold theorem

Mathematics Subject Classification ID

Medical applications (general) (92C50) Biochemistry, molecular biology (92C40)

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Cites work

• scientific article; zbMATH DE number 1581767 (Why is no real title available?)
• scientific article; zbMATH DE number 1467311 (Why is no real title available?)
• Analysis of tracer particle migration in inhomogeneous turbulence
• Mathematical modeling of the role of \textit{survivin} on dedifferentiation and radioresistance in cancer
• Multispecies model of cell lineages and feedback control in solid tumors
• The tumor growth paradox and immune system-mediated selection for cancer stem cells

Cited in

(11)

• Resilience analysis for competing populations
• Modelling of cancer stem cell driven solid tumors
• Feedback mechanisms control coexistence in a stem cell model of acute myeloid leukaemia
• Determining the control networks regulating stem cell lineages in colonic crypts
• Stability of control networks in autonomous homeostatic regulation of stem cell lineages
• Is the Allee effect relevant in cancer evolution and therapy?
• Mathematical modeling of the role of \textit{survivin} on dedifferentiation and radioresistance in cancer
• Effect of feedback regulation on stem cell fractions in tissues and tumors: understanding chemoresistance in cancer
• Dynamic analysis of a tumor-immune system under Allee effect
• Effect of cellular de-differentiation on the dynamics and evolution of tissue and tumor cells in mathematical models with feedback regulation
• Do mechanisms matter? Comparing cancer treatment strategies across mathematical models and outcome objectives

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