Concentration phenomenon in some non-local equation

DOI10.3934/DCDSB.2017037MaRDI QIDQ524045zbMATH OpenOpenAlexFDO

Authors O. Bonnefon, Jérôme Coville, Guillaume Legendre

Publication date 25 April 2017

Published in Discrete and Continuous Dynamical Systems. Series B (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/1510.01971

zbMATH Keywords

asymptotic behaviourconcentration phenomenonnon-local equationdemo-genetics

Mathematics Subject Classification ID

Problems related to evolution (92D15) Asymptotic behavior of solutions to PDEs (35B40) Integro-partial differential equations (45K05) Blow-up in context of PDEs (35B44) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Integro-partial differential equations (35R09)

Abstract: We are interested in the long time behaviour of the positive solutions of the Cauchy problem involving the following integro-differential equation ${\displaystyle }$partial_t u(t, x) = left(a(x) -- int_{Omega} k(x, y)u(t, y) dy ight ) u(t, x) + int_{Omega} m(x, y)[u(t, y) -- u(t, x)] dyquad ext{ for}quad (t, x) $in$ mathbb{R}_{+} imes Omega,${\displaystyle }$ together with the initial condition $u(0,cdot)=u0quadextinquadOmega$. Such a problem is used in population dynamics models to capture the evolution of a clonal population structured with respect to a phenotypic trait. In this context, the function u represents the density of individuals characterized by the trait, the domain of trait values $Omega$ is a bounded subset of $mathbb{R}^N$ , the kernels $k$ and $m$ respectively account for the competition between individuals and the mutations occurring in every generation, and the function a represents a growth rate. When the competition is independent of the trait, we construct a positive stationary solution which belongs to the space of Radon measures on $Omega$. Moreover, when this stationary measure is regular and bounded, we prove its uniqueness and show that, for any non negative initial datum in $L^{infty}(Omega)cap{L}^1(Omega)$, the solution of the Cauchy problem converges to this limit measure in $L^2(Omega)$. We also construct an example for which the measure is singular and non-unique, and investigate numerically the long time behaviour of the solution in such a situation. These numerical simulations seem to reveal some dependence of the limit measure with respect to the initial datum.

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Cited in

(14)

• Remarks on the spectrum of a non‐local Dirichlet problem
• Concentration estimates in a multi-host epidemiological model structured by phenotypic traits
• On the role of tumor heterogeneity for optimal cancer chemotherapy
• Steady state concentration for a phenotypic structured problem modeling the evolutionary epidemiology of spore producing pathogens
• Confining integro-differential equations originating from evolutionary biology: ground states and long time dynamics
• Slow convergence to equilibrium for an evolutionary epidemiology integro-differential system
• Linear theory for a mixed operator with Neumann conditions
• Measure framework for the pure selection equation: global well posedness and numerical investigations
• The Hadamard formula for nonlocal eigenvalue problems
• Asymptotic and transient behaviour for a nonlocal problem arising in population genetics
• Exponential quasi-ergodicity for processes with discontinuous trajectories
• (Non)local logistic equations with Neumann conditions
• Combination of direct methods and homotopy in numerical optimal control: application to the optimization of chemotherapy in cancer
• Singular measure traveling waves in an epidemiological model with continuous phenotypes

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