Optimal control of a multi-level dynamic model for biofuel production

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Publication:524826

DOI10.3934/MCRF.2017008zbMATH Open1360.49001arXiv1303.6688OpenAlexW2607048795MaRDI QIDQ524826FDOQ524826


Authors: R. Ghezzi, B. Piccoli Edit this on Wikidata


Publication date: 26 April 2017

Published in: Mathematical Control and Related Fields (Search for Journal in Brave)

Abstract: Dynamic flux balance analysis of a bioreactor is based on the coupling between a dynamic problem, which models the evolution of biomass, feeding substrates and metabolites, and a linear program, which encodes the metabolic activity inside cells. We cast the problem in the language of optimal control and propose a hybrid formulation to model the full coupling between macroscopic and microscopic level. On a given location of the hybrid system we analyze necessary conditions given by the Pontryagin Maximum Principle and discuss the presence of singular arcs. In particular, for the single-input case we prove that optimal controls are bang-bang. For the multi-input case, under suitable assumptions, we prove that generically with respect to initial conditions optimal controls are bang-bang.


Full work available at URL: https://arxiv.org/abs/1303.6688




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