The morbidostat: a bio-reactor that promotes selection for drug resistance in bacteria

DOI10.1137/16M105695XMaRDI QIDQ5346776zbMATH OpenOpenAlexFDO

Authors Zhenzhen Chen, Sze-Bi Hsu, Ya-Tang Yang

Publication date 29 May 2017

Published in SIAM Journal on Applied Mathematics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1137/16m105695x

zbMATH Keywords

coexistenceserial transfer dilutionmutantswild typeexclusion principlemorbidostat

Mathematics Subject Classification ID

Physiological, cellular and medical topics (92C99)

Recommendations

• The continuous morbidostat: a chemostat with controlled drug application to select for drug resistance mutants
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Cites work

• scientific article; zbMATH DE number 3247443 (Why is no real title available?)
• A Lotka-Volterra competition model with seasonal succession
• Analysis of a Model of Two Competitors in a Chemostat with an External Inhibitor
• Bacterial competition in serial transfer culture
• Dynamical systems and population persistence
• Ordinary differential equations with applications.
• The Theory of the Chemostat

Cited in

(5)

• The operating diagram of a model of two competitors in a chemostat with an external inhibitor
• Dynamic analysis of conversion from a drug-sensitivity strain to a drug-resistant strain
• The continuous morbidostat: a chemostat with controlled drug application to select for drug resistance mutants
• Dynamics of mathematical models for bioreactors. (Abstract of thesis)
• A spatio-temporal model of drug resistance in bacteria with mutations

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