Retroactivity Attenuation in Bio-Molecular Systems Based on Timescale Separation

DOI10.1109/TAC.2010.2069631zbMATH Open1368.93399MaRDI QIDQ5347665FDOQ5347665

Authors S. Jayanthi, Domitilla Del Vecchio 

Publication date 25 August 2017

Published in IEEE Transactions on Automatic Control (Search for Journal in Brave)

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Singular perturbations for ordinary differential equations (34E15) Dynamic equations on time scales or measure chains (34N05) Time-scale analysis and singular perturbations in control/observation systems (93C70)

Cited In (6)

• Layered decomposition for the model order reduction of timescale separated biochemical reaction networks
• Structural analysis in biology: a control-theoretic approach
• Physically-plausible modelling of biomolecular systems: a simplified, energy-based model of the mitochondrial electron transport chain
• Optimizing enzymatic catalysts for rapid turnover of substrates with low enzyme sequestration
• Singularly perturbed problems with multi-tempo fast variables
• The inverse correlation between robustness and sensitivity to autoregulation in two-component systems

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