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Uniformly minimum variance conditionally unbiased estimation in multi-arm multi-stage clinical trials

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Publication:5384602
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DOI10.1093/BIOMET/ASY004OpenAlexW2783875115MaRDI QIDQ5384602FDOQ5384602


Authors: Nigel Stallard, Peter K. Kimani Edit this on Wikidata


Publication date: 24 June 2019

Published in: Biometrika (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1093/biomet/asy004





zbMATH Keywords

point estimationtreatment selectiondrop-the-loser designadaptive seamless design


Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)



Cited In (6)

  • Adjusting for selection bias in assessing treatment effect estimates from multiple subgroups
  • A unified Bayesian framework for bias adjustment in multiple comparisons from clinical trials
  • Adaptive multiarm multistage clinical trials
  • To add or not to add a new treatment arm to a multiarm study: a decision-theoretic framework
  • Point estimation for adaptive trial designs. I: A methodological review
  • Adjusting for treatment selection in phase II/III clinical trials with time to event data





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