Statistical Reconstruction of Transcription Factor Activity Using Michaelis–Menten Kinetics

DOI10.1111/j.1541-0420.2007.00757.xzbMath1146.62090OpenAlexW2155465020WikidataQ51906419 ScholiaQ51906419MaRDI QIDQ5434914

V. Mersinias, Raya Khanin, C. P. Smith, Veronica Vinciotti, Ernst C. Wit

Publication date: 14 January 2008

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1111/j.1541-0420.2007.00757.x

zbMATH Keywords

maximum likelihood estimationMichaelis-Menten kineticsgene regulationStreptomyces coelicolor

Mathematics Subject Classification ID

Nonparametric hypothesis testing (62G10) Applications of statistics to biology and medical sciences; meta analysis (62P10) Point estimation (62F10) Biochemistry, molecular biology (92C40)

Related Items (3)

Effect of environmental stress on regulation of gene expression in the yeast ⋮ Time-course window estimator for ordinary differential equations linear in the parameters ⋮ Semiparametric mixed-effects ordinary differential equation models with heavy-tailed distributions

Cites Work

• Importance of replication in microarray gene expression studies: Statistical methods and evidence from repetitive cDNA hybridizations
• A Mixed Model Approach to Identify Yeast Transcriptional Regulatory Motifs via Microarray Experiments

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