Nonparametric sequential testing in clinical trials with incomplete multivariate observations
DOI10.1093/BIOMET/78.1.123zbMATH Open0717.62068OpenAlexW2024446781MaRDI QIDQ5748769FDOQ5748769
Authors: D. Y. Lin 
Publication date: 1991
Published in: Biometrika (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1093/biomet/78.1.123
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asymptotic powerlocal alternativesmartingaleinterim analysisAIDSrandomized clinical trialsmultiple endpointsasymptotic joint distributionrepeated significance testingoverall significance levelStopping boundariestime-to-event variablesweighted sum of the linear rank statistics
Nonparametric hypothesis testing (62G10) Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical analysis (62L10)
Cited In (15)
- Closed Testing Procedures for Group Sequential Clinical Trials with Multiple Endpoints
- An Adaptive Approach to Implementing Bivariate Group Sequential Clinical Trial Designs
- Title not available (Why is that?)
- Directional Tests for the Analysis of Clinical Trials with Multiple Endpoints Allowing for Incomplete Data
- Analyzing multiple end points with a two-stage design in clinical trials
- Completeness and unbiased estimation of mean vector in the multivariate group sequential case
- A Bayesian Group Sequential Approach for Multiple Endpoints
- On the efficiency of nonparametric variance estimation in sequential dose-finding
- An Introduction to Practical Sequential Inferences via Single-Arm Binary Response Studies Using the binseqtest R Package
- Confirmatory adaptive designs for clinical trials with multiple time-to-event outcomes in multi-state Markov models
- Advances in medical statistics arising from the AIDS epidemic
- Multistage nonparametric tests for treatment comparisons in clinical trials with multiple primary endpoints
- Nonparametric Rank‐Based Methods for Group Sequential Monitoring of Paired Censored Survival Data
- Title not available (Why is that?)
- Group-sequential logrank methods for trial designs using bivariate non-competing event-time outcomes
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