Spectral decomposition of atomic structures in heterogeneous cryo-EM

DOI10.1088/1361-6420/ACB2BAMaRDI QIDQ5876570zbMATH OpenOpenAlexFDO

Authors Carlos Esteve-Yagüe, Willem Diepeveen, Ozan Öktem, Carola-Bibiane Schönlieb

Publication date 1 February 2023

Published in Inverse Problems (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://arxiv.org/abs/2209.05546

zbMATH Keywords

graph Laplaciantomographic reconstructionatomic structure decompositionheterogeneous cryo-EM

Mathematics Subject Classification ID

Bayesian inference (62F15) Biochemistry, molecular biology (92C40) Nonconvex programming, global optimization (90C26) Biomedical imaging and signal processing (92C55) Electro- and magnetostatics (78A30) Biological applications of optics and electromagnetic theory (78A70) Inverse problems (including inverse scattering) in optics and electromagnetic theory (78A46) Atomic physics (81V45) Geometric optics (78A05)

Recommendations

• Hyper-molecules: on the representation and recovery of dynamical structures for applications in flexible macro-molecules in cryo-EM
• Cryo-EM reconstruction of continuous heterogeneity by Laplacian spectral volumes
• Covariance matrix estimation for the cryo-EM heterogeneity problem
• Viewing angle classification of cryo-electron microscopy images using eigenvectors
• Three-dimensional structure determination from common lines in cryo-EM by eigenvectors and semidefinite programming

Cites work

• A spectral series approach to high-dimensional nonparametric regression
• Consistency of spectral clustering
• Covariance matrix estimation for the cryo-EM heterogeneity problem
• Cryo-EM reconstruction of continuous heterogeneity by Laplacian spectral volumes
• Feasibility of tomography with unknown view angles
• Finding structure with randomness: probabilistic algorithms for constructing approximate matrix decompositions
• Geometrical structure of Laplacian eigenfunctions
• Le spectre d'une variété riemannienne. (The spectrum of a Riemannian manifold)
• On learning with integral operators
• Rapid solution of the cryo-EM reconstruction problem by frequency marching
• Structural variability from noisy tomographic projections
• Uniqueness of tomography with unknown view angles

Cited in

(3)

• Covariance matrix estimation for the cryo-EM heterogeneity problem
• Hyper-molecules: on the representation and recovery of dynamical structures for applications in flexible macro-molecules in cryo-EM
• Cryo-EM reconstruction of continuous heterogeneity by Laplacian spectral volumes

Describes a project that uses

Uses Software

• RELION

This page was built for publication: Spectral decomposition of atomic structures in heterogeneous cryo-EM

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q5876570)