On an extended interpretation of linkage disequilibrium in genetic case-control association studies

DOI10.1515/SAGMB-2015-0024zbMATH Open1330.92078OpenAlexW1866738438WikidataQ40387521 ScholiaQ40387521MaRDI QIDQ5962700FDOQ5962700

Authors: Thorsten Dickhaus, Jens Stange, Haydar Demirhan 

Publication date: 16 February 2016

Published in: Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1515/sagmb-2015-0024

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zbMATH Keywords

contingency tableFisher's exact testodds ratiocorrelation structureCochran-Armitage trend testchi-squared statisticDelta methodasymptotic Gaussianity

Mathematics Subject Classification ID

Parametric hypothesis testing (62F03) General biostatistics (92B15) Genetics and epigenetics (92D10)

Cites Work

• Title not available (Why is that?)
• Simultaneous Statistical Inference
• Title not available (Why is that?)
• On the Exact Covariance of Products of Random Variables
• Inferences about Linkage Disequilibrium
• A statistical approach to genetic epidemiology. Concepts and application. With a foreword by Robert C. Elston.

Cited In (7)

• Multiplicity- and dependency-adjusted \(p\)-values for control of the family-wise error rate
• New perspective on the benefits of the gene–environment independence in case–control studies
• Exploring case-control genetic association tests using phase diagrams
• Randomized ‐values for multiple testing and their application in replicability analysis
• Joint consideration of multiple loci and their influence on a disease in case-control studies
• Case-Control Inference of Interaction between Genetic and Nongenetic Risk Factors under Assumptions on Their Distribution
• Unified Analysis of Secondary Traits in Case–Control Association Studies

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