On the validity of within-nuclear-family genetic association analysis in samples of extended families

DOI10.1515/SAGMB-2015-0056zbMATH Open1330.92076OpenAlexW2322448335WikidataQ38602844 ScholiaQ38602844MaRDI QIDQ5962703FDOQ5962703

Authors: Alexandre Bureau, Thierry Duchesne 

Publication date: 16 February 2016

Published in: Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc4764343

Recommendations

• Estimating genetic association parameters from family data
• Use of Regression Models to Estimate Genetic Parameters and Measures of Familial Resemblance in Man
• Score tests of genetic association in the presence of linkage based on the additive genetic gamma frailty model
• Inference for covariates that accounts for ascertainment and random genetic effects in family studies
• Family based association study with complex survey data

zbMATH Keywords

conditional logistic regressionWald testgenetic linkageempirical variance estimationpseudo-controls

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Genetics and epigenetics (92D10)

Cites Work

• Title not available (Why is that?)
• A statistical approach to genetic epidemiology. Concepts and application. With a foreword by Robert C. Elston.
• Goodness-of-fit methods for matched case-control studies
• Inference Methods for the Conditional Logistic Regression Model with Longitudinal Data

Cited In (2)

• Estimating genetic association parameters from family data
• \texttt{Polyunphased}: an extension to polytomous outcomes of the unphased package for family-based genetic association analysis

Uses Software

• QRM
• UNPHASED
• PedGenie

This page was built for publication: On the validity of within-nuclear-family genetic association analysis in samples of extended families

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q5962703)