An age-of-infection model with both symptomatic and asymptomatic infections

DOI10.1007/S00285-023-01920-WzbMATH Open1512.92090arXiv2111.02343OpenAlexW4366998921MaRDI QIDQ6038685FDOQ6038685

Authors: Fan Bai 

Publication date: 2 May 2023

Published in: Journal of Mathematical Biology (Search for Journal in Brave)

Abstract: We formulate a general age-of-infection epidemic model with two pathways: the symptomatic infections and the asymptomatic infections. We then calculate the basic reproduction number $mathcal{R}_0$ and establish the final size relation. It is shown that the ratio of accumulated counts of symptomatic patients and asymptomatic patients is determined by the symptomatic ratio $f$ which is defined as the probability of eventually becoming symptomatic after being infected. We also formulate and study a general age-of-infection model with disease deaths and with two infection pathways. The final size relation is investigated, and the upper and lower bounds for final epidemic size are given. Several numerical simulations are performed to verify the analytical results.

Full work available at URL: https://arxiv.org/abs/2111.02343

Recommendations

• Final size for epidemic models with asymptomatic transmission
• Age-of-infection and the final size relation
• Who is the infector? Epidemic models with symptomatic and asymptomatic cases
• Age of infection epidemic models with heterogeneous mixing
• On the role of asymptomatic infection in transmission dynamics of infectious diseases

zbMATH Keywords

integro-differential equationsmathematical epidemiologyage of infection modelsdeterministic compartmental modelsfinal epidemic size estimation

Mathematics Subject Classification ID

Epidemiology (92D30) Integro-ordinary differential equations (45J05)

Cites Work

• Reproduction numbers and sub-threshold endemic equilibria for compartmental models of disease transmission
• Epidemiological models with non-exponentially distributed disease stages and applications to disease control
• On the asymptotic distribution of the size of a stochastic epidemic
• Mathematical models in population biology and epidemiology
• Mathematical epidemiology.
• Epidemic models with heterogeneous mixing and treatment
• Stochastic epidemic models: a survey
• The Kermack--McKendrick epidemic model revisited
• Age of infection epidemic models with heterogeneous mixing
• Age-of-infection and the final size relation
• Calculation of \({\mathcal R}_0\) for age-of-infection models
• Title not available (Why is that?)
• Mathematical and Statistical Modeling for Emerging and Re-emerging Infectious Diseases
• Mathematical models in epidemiology
• The effect of delay in viral production in within-host models during early infection

Cited In (6)

• Age-of-infection and the final size relation
• Reproduction number for an age of infection structured model
• The state-reproduction number for a multistate class age structured epidemic system and its application to the asymptomatic transmission model
• Who is the infector? Epidemic models with symptomatic and asymptomatic cases
• Mathematical modelling the age dependence of Epstein-Barr virus associated infectious mononucleosis
• Final size for epidemic models with asymptomatic transmission

This page was built for publication: An age-of-infection model with both symptomatic and asymptomatic infections

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q6038685)