The Hyperbolic-Parabolic Chemotaxis System for Vasculogenesis: Global Dynamics and Relaxation Limit Toward a Keller–Segel Model
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Publication:6073316
global well-posednessKeller-Segelrelaxation limitcritical regularityvascular networkoptimal time-decay ratehyperbolic-parabolic chemotaxis
Smoothness and regularity of solutions to PDEs (35B65) Existence problems for PDEs: global existence, local existence, non-existence (35A01) Uniqueness problems for PDEs: global uniqueness, local uniqueness, non-uniqueness (35A02) Blow-up in context of PDEs (35B44) Euler equations (35Q31) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Existence, uniqueness, and regularity theory for compressible fluids and gas dynamics (76N10) Cell movement (chemotaxis, etc.) (92C17) Cell biology (92C37) Rate of convergence, degree of approximation (41A25)
Abstract: An Euler-type hyperbolic-parabolic system of chemotactic aggregation describing the vascular network formation is investigated in the critical regularity setting. For small initial data around a constant equilibrium state, the well-posedness of the global classical solution to the Cauchy problem with general pressure laws is established in homogeneous hybrid Besov spaces. Then, the optimal time-decay rates of the global solution are analyzed under an additional regularity assumption on the initial data. Furthermore, the relaxation limit (large friction limit) of the hyperbolic-parabolic system is justified rigorously. It is shown that as the friction coefficient tends to zero, the global solution of the hyperbolic-parabolic chemotaxis system converges to the global solution of the Keller-Segel equations with an explicit convergence rate. To capture the dissipative properties of the nonlinear system, our approach relies on the introduction of new effective unknowns in low frequencies and the construction of a Lyapunov functional in the spirit of Beauchard and Zuazua's in [5] to treat the high frequencies.
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Cited in
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