Where to locate <scp>COVID</scp>‐19 mass vaccination facilities?

DOI10.1002/NAV.22007MaRDI QIDQ6077337zbMATH OpenFDO

Authors Dimitris Bertsimas, Vassilis jun. Digalakis, Alexandre Jacquillat, Michael Lingzhi Li

Publication date 18 October 2023

Published in Naval Research Logistics (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/2102.07309

zbMATH Keywords

COVID-19epidemiological modelingnonconvex optimizationvaccine distribution

Mathematics Subject Classification ID

Management decision making, including multiple objectives (90B50) Discrete location and assignment (90B80) Nonconvex programming, global optimization (90C26) Epidemiology (92D30)

Abstract: The outbreak of COVID-19 led to a record-breaking race to develop a vaccine. However, the limited vaccine capacity creates another massive challenge: how to distribute vaccines to mitigate the near-end impact of the pandemic? In the United States in particular, the new Biden administration is launching mass vaccination sites across the country, raising the obvious question of where to locate these clinics to maximize the effectiveness of the vaccination campaign. This paper tackles this question with a novel data-driven approach to optimize COVID-19 vaccine distribution. We first augment a state-of-the-art epidemiological model, called DELPHI, to capture the effects of vaccinations and the variability in mortality rates across age groups. We then integrate this predictive model into a prescriptive model to optimize the location of vaccination sites and subsequent vaccine allocation. The model is formulated as a bilinear, non-convex optimization model. To solve it, we propose a coordinate descent algorithm that iterates between optimizing vaccine distribution and simulating the dynamics of the pandemic. As compared to benchmarks based on demographic and epidemiological information, the proposed optimization approach increases the effectiveness of the vaccination campaign by an estimated $20\mathrm{\%}$, saving an extra $4000$ extra lives in the United States over a three-month period. The proposed solution achieves critical fairness objectives -- by reducing the death toll of the pandemic in several states without hurting others -- and is highly robust to uncertainties and forecast errors -- by achieving similar benefits under a vast range of perturbations.

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Cites work

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Cited in

(19)

• Dynamic planning of a two-dose vaccination campaign with uncertain supplies
• Resource distribution under spatiotemporal uncertainty of disease spread: stochastic versus robust approaches
• Safe distancing in the time of COVID-19
• Testing facility location and dynamic capacity planning for pandemics with demand uncertainty
• Stochastic optimization for vaccine and testing kit allocation for the COVID-19 pandemic
• On the mass COVID-19 vaccination scheduling problem
• The optimal allocation of Covid-19 vaccines
• A two-stages mathematical model for a Covid-19 vaccination fuzzy scheme and resource allocation in hub locations considering transmission risk and environment factor
• Optimizing influenza vaccine composition: A machine learning approach
• Quantifying the benefits of customized vaccination strategies: A network‐based optimization approach
• Spatiotemporal vaccine allocation policies for epidemics with behavioral feedback dynamics
• Optimizing vaccine distribution in developing countries under natural disaster risk
• Fair-split distribution of multi-dose vaccines with prioritized age groups and dynamic demand: the case study of COVID-19
• A data-driven spatially-specific vaccine allocation framework for COVID-19
• Bi-objective model for the distribution of COVID-19 vaccines
• Optimization modeling for pandemic vaccine supply chain management: a review and future research opportunities
• A decision-making framework for supporting an equitable global vaccine distribution under humanitarian perspectives
• Navigating the waves: the global pandemic's impact on container shipping and freight rates across different policy scenarios
• Optimizing vaccine logistics: a taxonomy and narrative review

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