Optimization of vaccination for COVID-19 in the midst of a pandemic
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Publication:2087007
DOI10.3934/NHM.2022016zbMATH Open1501.92087arXiv2203.09502OpenAlexW4225648523MaRDI QIDQ2087007FDOQ2087007
Authors: Qi Luo, Ryan Weightman, Sean T. McQuade, Mateo Díaz, William Barbour, Dan Work, Samitha Samaranayake, B. Piccoli, Emmanuel Trélat 
Publication date: 26 October 2022
Published in: Networks and Heterogeneous Media (Search for Journal in Brave)
Abstract: During the Covid-19 pandemic a key role is played by vaccination to combat the virus. There are many possible policies for prioritizing vaccines, and different criteria for optimization: minimize death, time to herd immunity, functioning of the health system. Using an age-structured population compartmental finite-dimensional optimal control model, our results suggest that the eldest to youngest vaccination policy is optimal to minimize deaths. Our model includes the possible infection of vaccinated populations. We apply our model to real-life data from the US Census for New Jersey and Florida, which have a significantly different population structure. We also provide various estimates of the number of lives saved by optimizing the vaccine schedule and compared to no vaccination.
Full work available at URL: https://arxiv.org/abs/2203.09502
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Medical epidemiology (92C60) Existence theories for optimal control problems involving ordinary differential equations (49J15)
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Cited In (26)
- On the mass COVID-19 vaccination scheduling problem
- Age structured mathematical modeling studies on COVID-19 with respect to combined vaccination and medical treatment strategies
- How to coordinate vaccination and social distancing to mitigate SARS-CoV-2 outbreaks
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