Well posedness and control in a nonlocal SIR model

DOI10.1007/S00245-020-09660-9MaRDI QIDQ2045136zbMATH OpenOpenAlexFDO

Authors Mauro Garavello, R. M. Colombo

Publication date 11 August 2021

Published in Applied Mathematics and Optimization (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/1910.07389

zbMATH Keywords

vaccinationcontrol in age-structured populations modelsoptimal control of balance laws

Mathematics Subject Classification ID

Epidemiology (92D30) Initial-boundary value problems for first-order hyperbolic systems (35L50) Hyperbolic conservation laws (35L65) Existence theories for optimal control problems involving partial differential equations (49J20)

Abstract: SIR models, also with age structure, can be used to describe the evolution of an infective disease. A vaccination campaign influences this dynamics immunizing part of the susceptible individuals, essentially turning them into recovered individuals. We assume that vaccinations are dosed at prescribed times or ages which introduce discontinuities in the evolutions of the S and R populations. It is then natural to seek the 'best' vaccination strategies in terms of costs and/or effectiveness. This paper provides the basic well posedness and stability results on the SIR model with vaccination campaigns, thus ensuring the existence of optimal dosing strategies.

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Cited in

(11)

• Using a stochastic SIR model to design optimal vaccination campaigns via multiobjective optimization
• Optimizing vaccination strategies in an age structured SIR model
• A measure model for the spread of viral infections with mutations
• Modeling multilane traffic with moving obstacles by nonlocal balance laws
• Control of COVID-19 outbreak using an extended SEIR model
• Control methods in hyperbolic PDEs. Abstracts from the workshop held November 5--10, 2023
• Coupling compartmental models with Markov chains and measure evolution equations to capture virus mutability
• Optimization of vaccination for COVID-19 in the midst of a pandemic
• The COVID-19 Pandemic Evolution in Hawai‘i and New Jersey: A Lesson on Infection Transmissibility and the Role of Human Behavior
• On the coupling of well posed differential models
• Vaccination strategies through intra-compartmental dynamics

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