Causal interaction trees: Finding subgroups with heterogeneous treatment effects in observational data
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Publication:6079481
Abstract: We propose Causal Interaction Trees for identifying subgroups of participants that have enhanced treatment effects using observational data. We extend the Classification and Regression Tree algorithm by using splitting criteria that focus on maximizing between-group treatment effect heterogeneity based on subgroup-specific treatment effect estimators to dictate decision-making in the algorithm. We derive properties of three subgroup-specific treatment effect estimators that account for the observational nature of the data -- inverse probability weighting, g-formula and doubly robust estimators. We study the performance of the proposed algorithms using simulations and implement the algorithms in an observational study that evaluates the effectiveness of right heart catheterization on critically ill patients.
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- scientific article; zbMATH DE number 3860199 (Why is no real title available?)
- scientific article; zbMATH DE number 6276204 (Why is no real title available?)
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Cited in
(15)- Subgroup causal effect identification and estimation via matching tree
- Efficient Targeted Learning of Heterogeneous Treatment Effects for Multiple Subgroups
- An exploratory data analysis for average treatment effect estimation based on partial balancing and simultaneous inference of regression models
- Bayesian regression tree models for causal inference: regularization, confounding, and heterogeneous effects (with discussion)
- Tree-structured analysis of treatment effects with large observational data
- Recursive partitioning for heterogeneous causal effects
- Distributed identification of heterogeneous treatment effects
- A comparison of five recursive partitioning methods to find person subgroups involved in meaningful treatment-subgroup interactions
- Regularized outcome weighted subgroup identification for differential treatment effects
- Subgroup analysis using Bernoulli‐gated hierarchical mixtures of experts models
- Subgroup analysis for longitudinal data based on a partial linear varying coefficient model with a change plane
- Modern approaches for evaluating treatment effect heterogeneity from clinical trials and observational data
- Shrinkage Bayesian Causal Forests for Heterogeneous Treatment Effects Estimation
- Sensitivity analysis using bias functions for studies extending inferences from a randomized trial to a target population
- scientific article; zbMATH DE number 6276204 (Why is no real title available?)
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