Mitochondrial outer membrane permeabilization and inner membrane permeabilization in regulating apoptosis and inflammation

DOI10.1016/J.JTBI.2023.111558MaRDI QIDQ6136951zbMATH OpenOpenAlexFDO

Authors Hong Qi, Yu-Song Yin, Zhiyong Yin, Xiang Li, J. W. Shuai

Publication date 31 August 2023

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2023.111558

zbMATH Keywords

apoptosisinflammationdynamic mechanismmitochondrial inner membrane permeabilizationmitochondrial outer membrane permeabilization

Mathematics Subject Classification ID

Cell biology (92C37) Pathology, pathophysiology (92C32)

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Cites work

• Bifurcation and sensitivity analysis reveal key drivers of multistability in a model of macrophage polarization
• Signalling-modulated gene regulatory networks in early mammalian development

Cited in

(2)

• Molecular modeling of BAD complex resided in a mitochondrion integrating glycolysis and apoptosis
• The Bcl-2-associated death promoter (BAD) lowers the threshold at which the Bcl-2-interacting domain death agonist (BID) triggers mitochondria disintegration

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