Mitochondrial outer membrane permeabilization and inner membrane permeabilization in regulating apoptosis and inflammation

DOI10.1016/J.JTBI.2023.111558zbMATH Open1520.92028OpenAlexW4380792615MaRDI QIDQ6136951FDOQ6136951

Authors: Hong Qi, Yu-Song Yin, Zhiyong Yin, Xiang Li, J. W. Shuai 

Publication date: 31 August 2023

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2023.111558

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zbMATH Keywords

apoptosisinflammationdynamic mechanismmitochondrial inner membrane permeabilizationmitochondrial outer membrane permeabilization

Mathematics Subject Classification ID

Cell biology (92C37) Pathology, pathophysiology (92C32)

Cites Work

• Signalling-modulated gene regulatory networks in early mammalian development
• Bifurcation and sensitivity analysis reveal key drivers of multistability in a model of macrophage polarization

Cited In (2)

• Molecular modeling of BAD complex resided in a mitochondrion integrating glycolysis and apoptosis
• The Bcl-2-associated death promoter (BAD) lowers the threshold at which the Bcl-2-interacting domain death agonist (BID) triggers mitochondria disintegration

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