Homogenization theory of ion transportation in multicellular tissue

DOI10.3934/DCDSB.2023072MaRDI QIDQ6156570zbMATH OpenOpenAlexFDO

Authors Chun Xiao, Huaxiong Huang, Shixin Xu, Tao Yu, Xingye Yue

Publication date 13 June 2023

Published in Discrete and Continuous Dynamical Systems. Series B (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/2103.06019

zbMATH Keywords

connectivityion transportunfolding operatorbi-domain model

Mathematics Subject Classification ID

Asymptotic behavior of solutions to PDEs (35B40) A priori estimates in context of PDEs (35B45) Smoothness and regularity of solutions to PDEs (35B65) Existence problems for PDEs: global existence, local existence, non-existence (35A01) Uniqueness problems for PDEs: global uniqueness, local uniqueness, non-uniqueness (35A02) Homogenization in context of PDEs; PDEs in media with periodic structure (35B27) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Motion of charged particles (78A35) Biophysics (92C05) Cell biology (92C37)

Abstract: Ion transport in biological tissues is crucial in the study of many biological and pathological problems. Some multi-cellular structures, like smooth muscles on the vessel walls, could be treated as periodic bi-domain structures, which consist of intracellular space and extracellular space with semipermeable membranes in between. With the aid of two-scale homogenization theory, macro-scale models are proposed based on an electro-neutral (EN) microscale model with nonlinear interface conditions, where membranes are treated as combinations of capacitors and resistors. The connectivity of intracellular space is also taken into consideration. If the intracellular space is fully connected and forms a syncytium, then the macroscale model is a bidomain nonlinear coupled partial differential equations system. Otherwise, when the intracellular cells are not connected, the macroscale model for intracellular space is an ordinary differential system with source/sink terms from the connected extracellular space.

Recommendations

• Multiscale analysis of ionic transport in periodic charged media
• Homogenization of oxygen transport in biological tissues
• On a hierarchy of models for electrical conduction in biological tissues
• A three-dimensional model of cellular electrical activity
• Unfolding homogenization method applied to physiological and phenomenological bidomain models in electrocardiology

Cites work

• scientific article; zbMATH DE number 5178712 (Why is no real title available?)
• scientific article; zbMATH DE number 1375522 (Why is no real title available?)
• scientific article; zbMATH DE number 2062995 (Why is no real title available?)
• scientific article; zbMATH DE number 2139393 (Why is no real title available?)
• scientific article; zbMATH DE number 3222151 (Why is no real title available?)
• A General Convergence Result for a Functional Related to the Theory of Homogenization
• A note on the existence of extension operators for Sobolev spaces on periodic domains
• Adaptive Mesh Methods for One- and Two-Dimensional Hyperbolic Conservation Laws
• Corrector results for a parabolic problem with a memory effect
• Correctors for the Homogenization of a Class of Hyperbolic Equations with Imperfect Interfaces
• Derivation of the Double Porosity Model of Single Phase Flow via Homogenization Theory
• HOMOGENIZATION OF TWO HEAT CONDUCTORS WITH AN INTERFACIAL CONTACT RESISTANCE
• Homogenization and Two-Scale Convergence
• Homogenization and correctors for the hyperbolic problems with imperfect interfaces via the periodic unfolding method
• Homogenization for chemical vapor infiltration process
• Homogenization of a nonlinear multiscale model of calcium dynamics in biological cells
• Homogenization of a parabolic problem with an imperfect interface
• Homogenization of reaction-diffusion processes in a two-component porous medium with nonlinear flux conditions at the interface
• Homogenization of the Poisson--Nernst--Planck equations for Ion Transport in Charged Porous Media
• Homogenization of the generalized Poisson-Nernst-Planck problem in a two-phase medium: correctors and estimates
• Homogenization of the linearized ionic transport equations in rigid periodic porous media
• Homogenization results for ionic transport in periodic porous media
• Ion transport through deformable porous media: derivation of the macroscopic equations using upscaling
• Moving Mesh Methods for Problems with Blow-Up
• Periodic unfolding and homogenization
• The Periodic Unfolding Method in Homogenization
• The periodic unfolding method for a class of imperfect transmission problems
• The periodic unfolding method for a class of parabolic problems with imperfect interfaces
• The periodic unfolding method for perforated domains and Neumann sieve models
• The periodic unfolding method in perforated domains
• Upscaling of a parabolic system with a large nonlinear surface reaction term

Cited in

(8)

• scientific article; zbMATH DE number 5262810 (Why is no real title available?)
• Computational modeling of membrane blockage via precipitation: a 2D extended Poisson-Nernst-Planck model
• Multiscale analysis of ionic transport in periodic charged media
• Theoretical modeling of fluid flow in cellular biological media: an overview
• Letter to the editor: Evolutionary determinants of the concentrations of inorganic ions in body fluids
• Fluid-solid mixtures and electrochemomechanics: the simplicity of Lagrangian mixture theory
• Mass transport in biological tissues: comparisons between single- and dual-porosity models in the context of saline-infused radiofrequency ablation
• Cellular communication among smooth muscle cells: the role of membrane potential via connexins

This page was built for publication: Homogenization theory of ion transportation in multicellular tissue

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q6156570)