On the use of a coupled mathematical model for understanding the dynamics of multiple sclerosis

DOI10.1016/J.CAM.2023.115163MaRDI QIDQ6169728zbMATH OpenOpenAlexFDO

Authors Matheus Avila Moreira de Paula, Bárbara de Melo Quintela, Marcelo Lobosco

Publication date 12 July 2023

Published in Journal of Computational and Applied Mathematics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.cam.2023.115163

zbMATH Keywords

computational modellingmultiple sclerosiscomputational immunology

Mathematics Subject Classification ID

PDEs in connection with biology, chemistry and other natural sciences (35Q92) Pathology, pathophysiology (92C32)

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Cites work

• Demyelination patterns in a mathematical model of multiple sclerosis
• Dynamical properties of autoimmune disease models: tolerance, flare-up, dormancy
• Immunological self-tolerance: Lessons from mathematical modeling
• Self-tolerance and autoimmunity in a regulatory T cell model
• Tolerance and immunity in a mathematical model of T-cell mediated suppression

Cited in

(11)

• Mesoscopic model of neuronal system deficits in multiple sclerosis
• Simulation of spread and control of lesions in brain
• Insights from mathematical modelling for T cell migration into the central nervous system
• Statistical Method for Analysis of the Disease Curve in Animals with Experimental Autoimmune Encephalomyelitis
• The dynamics of relapses during treatment switch in relapsing-remitting multiple sclerosis
• Distributed identification based partially-coupled recursive generalized extended least squares algorithm for multivariate input-output-error systems with colored noises from observation data
• Reaction-diffusion systems derived from kinetic theory for multiple sclerosis
• Is Multiple Sclerosis an Infectious Disease? Inference about an Input Process Based on the Output
• Multiple sclerosis plaques on nervous pathways: a computational model using neural networks
• A minimal unified model of disease trajectories captures hallmarks of multiple sclerosis
• Could mathematics be the key to unlocking the mysteries of multiple sclerosis?

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